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410,411 Remarkably, patients with HER2+ advanced breast cancer achieved a significantly longer PFS using trastuzumab deruxtecan (T-DXd) than T-DM1 in the DESTINY-Breast03 trial

7 29,500 27,500 Price range: 27,500 through 29,500 7 29,500 27,500 Price range: 27,500 through 29,500 7 14,200 12,200 Price range: 12,200 through 14,200 7 32,000 30,000 Price range: 30,000 through 32,000 7 32,000 30,000 Price range: 30,000 through 32,000 7 14,000 7 39,000 7 39,000 8 42,000 8 42,000 10 5/5 48,000 12,000 ( ) 12,000 25,700 13,000 27,500 27,500 7 ( ) 33,000 7 ( ) 33,000 7 ( ) 33,000 7 ( ) 33,000 8 ( ) 11,500 8 ( ) 11,500 8 ( ) 11,500 8 ( ) 11,500 5/5 7,200 6,200 Price range: 6,200 through 7,200 5/5 ( ) 7,200 6,200 Price range: 6,200 through 7,200 5/5 15,400 14,400 Price range: 14,400 through 15,400 5/5 16,400 15,400 Price range: 15,400 through 16,400 15,000 ( ) 15,000 32,000 13,500 ( ) 13,500 25,000 5/5 12,000 5/5 ( ) 12,000 5/5 20,000 5/5 13,000 5/5 ( ) 13,000 5/5 21,000 8 20,000 8 ( ) 20,000 8 33,000 8 22,000 8 ( ) 22,000 8 35,000 20 26,000 20 ( ) 26,000 20 46,000 25 47,000 25 ( ) 47,000 25 80,000 20 44,000 40,000 Price range: 40,000 through 44,000 20 ( ) 44,000 40,000 Price range: 40,000 through 44,000 20 74,000 70,000 Price range: 70,000 through 74,000 5/5 6,500 5,500 Price range: 5,500 through 6,500 8 ( ) 11,500 7 ( ) 33,000 7 13,000 11,000 Price range: 11,000 through 13,000 12,000 7 14,800 12,800 Price range: 12,800 through 14,800 7 32,000 30,000 Price range: 30,000 through 32,000 8 12,200 10,500 Price range: 10,500 through 12,200 8 ( ) 11,500 10 5/5 48,000 5/5 10,500 7 ( ) 33,000 25,700 7 14,200 12,200 Price range: 12,200 through 14,200 7 39,000 5/5 ( ) 7,200 6,200 Price range: 6,200 through 7,200 8 ( ) 11,500 5/5 9,000 8 10,700 9,000 Price range: 9,000 through 10,700 8 16,000 7 29,500 27,500 Price range: 27,500 through 29,500 5/5 7,300 6,300 Price range: 6,300 through 7,300 13,000 10 5/5 25,000 5/5 7,200 6,200 Price range: 6,200 through 7,200 10 5/5 10,500 8 14,700 13,000 Price range: 13,000 through 14,700 26,000 23,000 Price range: 23,000 through 26,000 8 26,200 24,500 Price range: 24,500 through 26,200 8 ( ) 11,500 27,500 10 5/5 11,500 7 29,500 27,500 Price range: 27,500 through 29,500 27,500 7 ( ) 33,000 8 13,700 12,000 Price range: 12,000 through 13,700 7 ( ) 33,000 8 42,000 7 32,000 30,000 Price range: 30,000 through 32,000 8 11,700 10,000 Price range: 10,000 through 11,700 10 5/5 9,500 ( ) 12,000 29,000 26,000 Price range: 26,000 through 29,000 8 15,000 8 42,000 5/5 16,400 15,400 Price range: 15,400 through 16,400 8 14,000 7 14,000 7 39,000 5/5 9,600 8,600 Price range: 8,600 through 9,600 5/5 10,500 5/5 21,500 5/5 ( ) 12,000 8 ( ) 14,000 5/5 13,000 7 14,000 20 ( ) 44,000 40,000 Price range: 40,000 through 44,000 ( ) 15,000 8 13,700 12,000 Price range: 12,000 through 13,700 5/5 12,000 8 24,400 22,700 Price range: 22,700 through 24,400 20 ( ) 26,000 13,500 8 32,000 5/5 ( ) 6,500 5,500 Price range: 5,500 through 6,500 5/5 8,800 7,800 Price range: 7,800 through 8,800 25 80,000 15,000 20 74,000 70,000 Price range: 70,000 through 74,000 25 ( ) 47,000 20 44,000 40,000 Price range: 40,000 through 44,000 10 ( ) 5/5 9,500 10 4 7,200 25 47,000 5/5 14,600 13,600 Price range: 13,600 through 14,600 7 39,000 8 22,000 8 35,000 25,000 8 ( ) 20,000 7 39,000 20 46,000 5/5 21,000 8 ( ) 22,000 8 33,000 7 18,700 16,700 Price range: 16,700 through 18,700 8 ( ) 10,700 9,000 Price range: 9,000 through 10,700 10 ( ) 4 7,200 8 20,000 5/5 8,200 7,200 Price range: 7,200 through 8,200 5/5 ( ) 9,000 10 4 18,000 10 4 8,000 7 34,000 32,000 Price range: 32,000 through 34,000 32,000 7 14,200 12,200 Price range: 12,200 through 14,200 8 14,700 13,000 Price range: 13,000 through 14,700 20 26,000 5/5 ( ) 13,000 7 ( ) 13,000 11,000 Price range: 11,000 through 13,000 10 5/5 25,000 7 16,900 14,900 Price range: 14,900 through 16,900 10 5/5 48,000 ( ) 26,000 23,000 Price range: 23,000 through 26,000 ( ) 13,500 5/5 20,000 10 4 8,000 8 16,400 14,700 Price range: 14,700 through 16,400

The reconstitution arithmetic itself is set out in the handling section further down this page